- Alternate costumes
Successfully complete the indicated task to unlock the corresponding costume:
| Rebacca (Nurse) | Get an 'S' rank in all missions, except Level Ex. | | Chris (Pilot) | Get an 'SS' rank in Mission 1-3. Alternately, get get 10 medals. | | Hunk (Reaper) | Get an 'A' rank in all missions, except Level Ex. | | Jill (Resident Evil 3) | Get an 'S' rank in Mission 3-5. | | Barry (American) | Get 20 medals. | | Krauser (Exoskaleton) | Get an 'S' rank in Mission 5-5. | | | | Claire (Suit) | Get 25 medals. | | | | Wesker (Uroboros) | Get a 'B' rank or higher in all missions. |
- Medals
Successfully complete the indicated task to unlock the corresponding medal:
| S.T.A.R.S. | Get an 'A' or better rank in all missions. | | Initiatener | Get a 'B' or better rank in Missions 2-1, 2-2, and 2-3. | | Newcomer | Get a 'B' or better rank in Missions 1-1, 1-2, and 1-3. | | Hero | Get a 'B' or better rank in Mission 5-5 to unlock the Ex missions. Then, get a 'B' or better rank in Missions Ex-1, Ex-2, Ex-3, Ex-4, Ex-5, Ex-6, Ex-7, Ex-8, and Ex-9. | | Rookie | Get a 'B' or better rank in Missions 3-1, 3-2, 3-3, 3-4, and 3-5. | | | | Captain | Get a 'B' or better rank in Missions 5-1, 5-2, 5-3, 5-4, and 5-5. | | | | Veteran | Get a 'B' or better rank in Missions 4-1, 4-2, 4-3, 4-4, and 4-5. |
- Weapon loadouts
Get an 'A' or better rank on all missions up to Mission 5-5. You will unlock that character's weapon loadout for use by any other character.
- Bonus characters
Successfully complete the indicated task to unlock the corresponding character:
| Rebecca | Successfully complete Mission 2-3 with a 'B' rank or higher. | | Claire | Successfully complete Mission 1-3 with a 'B' rank or higher. | | Barry | Successfully complete Mission 4-5 with a 'B' rank or higher. | | Krauser | Successfully complete Mission 3-5 with a 'B' rank or higher. | | | | | | Wesker | Successfully complete Mission 5-5 with a 'B' rank or higher. |
- EX missions
Successfully complete Mission 5-5 with a 'B' rank or higher to unlock the EX missions after the credits end.
- Bonus skills
Successfully complete the indicated task to unlock the corresponding skill:
| Toughness | Get the 'Like A Phoenix' medal. | | Maximizer | Successfully complete Mission 4-4 with a 'B' rank. | | Bomber | Successfully complete Mission 5-2 with a 'B' rank. | | Close Range | Successfully complete Mission level 4-3 with an 'S' rank. | | Reversal | Successfully complete Mission 5-4 with an 'S' rank. | | Full Burst | Successfully complete Mission EX-6 with a 'B' rank. | | Infinity 7 | Get 30 medals. | | Combat | Successfully complete Mission 4-2 with an 'S' rank. | | Shotgun Technique | Successfully complete Mission 5-1 with an 'S' rank. | | Handgun Custom | Successfully complete Mission EX-1 with a 'B' rank. | | Technician | Successfully complete Mission 5-3 with an 'S' rank. | | Magnum Technique | Successfully complete Mission 5-2 with an 'S' rank. | | Friendship | Get the 'Social Butterfly' medal. | | Shotgun Custom | Successfully complete Mission EX-5 with a 'B' rank. | | Lucky 7 | Successfully complete Mission 5-3 with a 'B' rank. | | Extension | Successfully complete Mission 4-1 with an 'S' rank. | | Machine Gun Technique | Successfully complete Mission 4-3 with a 'B' rank. | | Smart Reload | Successfully complete Mission EX-4 with a 'B' rank. | | Thunderbolt | Successfully complete Mission EX-7 with a 'B' rank. | | Medic | Successfully complete Mission 1-3 with a 'B' rank. | | Adrenaline | Successfully complete Mission 5-4 with a 'B' rank. | | Handgun Technique | Successfully complete Mission 4-1 with a 'B' rank. | | Giant Killing | Successfully complete Mission 4-5 with an 'S' rank. | | | | Rifle Technique | Successfully complete Mission 5-1 with a 'B' rank. | | Revenge | Successfully complete Mission 4-2 with a 'B' rank. | | Machine Gun Custom | Successfully complete Mission EX-2 with a 'B' rank. | | | | Weapon Master | Successfully complete Mission EX-8 with a 'B' rank. |
- Signature weapons
To make a character's signature weapons available for all other characters, get an 'S' rank using that character on all missions up to Mission 5-5. Alternately, you can spend 10 Nintendo 3DS Play Coins to unlock a character's weapons. |
